sunny moon 发布了更新 1年， 11个月 之前
Background of Epigenetics:
There is far more to genetics than the sequence of building blocks in the DNA molecules that make up our genes and chromosomes. The “more” is known as epigenetics.
What is epigenetics?
Epigenetics, literally “on” genes, refers to all modifications to genes other than changes in the DNA sequence itself. Epigenetic modifications include addition of molecules, like methyl groups, to the DNA backbone. Adding these groups changes the appearance and structure of DNA, altering how a gene can interact with important interpreting (transcribing) molecules in the cell’s nucleus.
How do epigenetic modifications affect genes?
Genes carry the blueprints to make proteins in the cell. The DNA sequence of a gene is transcribed into RNA, which is then translated into the sequence of a protein. Every cell in the body has the same genetic information; what makes cells, tissues and organs different is that different sets of genes are turned on or expressed.